Welcome to the Fang Lab Homepage!
Our lab is generally interested in neurobiology of human disease. Specifically, our research focuses on the fundamental mechanisms underlying the maintenance of the nervous system and the molecular and cellular processes that lead to axon degeneration in neural injury as well as age-related neurodegenerative diseases, such as ALS, AD, PD, etc.
Here, we apply molecular genetics, cell biology, pharmacology, in vivo fluorescent imaging, and evolving high-throughput RNA-seq and mass spec-based proteomic and metabolomic approaches to define genes and pathways that regulate neurodegeneration. In doing so, we hope to uncover evolutionarily conserved core programs that control neural integrity, which will provide the foundation for identifying and developing novel therapeutic strategies to delay, mitigate, prevent or even reverse neurodegeneration in injury and disease.
General Research and Teaching Interests
Neural Injury and Axon De/Re-generation
Neurobiology of Human Disease
Aging and Neurodegeneration
Cellular and Molecular Neuroscience
Molecular Genetics