学历: 博士研究生
邮箱: jiangzhu@sioc.ac.cn
电话:
地址: 上海市浦东新区海科路100号邮编:201210
2002-2006,南京大学化学系,获理学学士学位
2006-2011,美国马萨诸塞大学阿默斯特分校(UMass-Amherst),获哲学博士学位
2011-2013,美国加州斯克利普斯(Scripps)研究所,博士后
2013.9-至今 中国科学院生物与化学交叉研究中心 研究员、课题组长
朱正江课题组主要发展基于质谱技术的代谢组学新方法,并将代谢组学技术应用于研究与健康、疾病相关的生命医学问题。具体方向为
(1)发展新型质谱方法结合生物信息学实现高通量、全定量代谢组学技术;
(2)代谢组学生物信息学平台及代谢物数据库建设;
(3)运用代谢组学技术研究衰老及神经退行性疾病
1. M. Luo,Y. Yin,Z. Zhou,H. Zhang,X. Chen,H. Wang,and Z.-J. Zhu*, A Mass Spectrum-oriented Computational Method for Ion Mobility-resolved Untargeted Metabolomics, Nature Communications,2023,14: 1813.
2. H. Wang†,H. Jia†,Y. Gao,H. Zhang,J. Fan,L. Zhang,F. Ren,Y. Yin,Y. Cai*,J. Zhu*,and Z.-J. Zhu*, Serum Metabolic Traits Reveal Therapeutic Toxicities and Responses of Neoadjuvant Chemoradiotherapy in Patients with Rectal Cancer, Nature Communications, 2022,13: 7802.
3. Z. Zhou†,M. Luo†,H. Zhang, Y. Yin,Y. Cai,and Z.-J. Zhu* , Metabolite Annotation from Knowns to Unknowns through Knowledge-guided Multi-layer Metabolic Networking, Nature Communications, 2022,13: 6656.
4. R. Wang,Y. Yin,J. Li,H. Wang,W. Lv,Y. Gao,T. Wang,Y. Zhong,Z. Zhou,Y. Cai,X. Su,N. Liu*,and Z.-J. Zhu*,Global Stable-isotope Tracing Metabolomics Reveals System-wide Metabolic Alternations in Aging Drosophila, Nature Communications,2022,13: 3518.
5. X. Mei†,Y. Guo†,Z. Xie†,Y. Zhong,X. Wu,D. Xu,Y. Li,N. Liu,and Z.-J. Zhu*,RIPK1 Regulates Starvation Resistance by Modulating Aspartate Catabolism, Nature Communications,2021,12: 6144.
6. T. Li,Y. Yin,Z. Zhou,J. Qiu,W. Liu,X. Zhang,K. He,Y. Cai,and Z.-J. Zhu*, Ion Mobility-based Sterolomics Reveals Spatially and Temporally Distinctive Sterol Lipids in the Mouse Brain, Nature Communications,2021,12: 4343.
7. Z. Zhou,M. Luo,X. Chen,Y. Yin,X. Xiong,R. Wang,and Z.-J. Zhu*,Ion Mobility Collision Cross-Section Atlas for Known and Unknown Metabolite Annotation in Untargeted Metabolomics,Nature Communications,2020,11: 4334.
8. X. Shen,R. Wang,X. Xiong,Y. Yin,Y. Cai,Z. Ma,N. Liu,and Z.-J. Zhu*,Metabolic Reaction Network-based Recursive Metabolite Annotation for Untargeted Metabolomics, Nature Communications,2019,10: 1516.