· Cellular and molecular organization of the enteric nervous system, local information-processing mechanisms, and their physiological and pathological functions.

· Neural-circuit mechanisms of bidirectional brain-organ communication, including interoceptive sensory input and autonomic regulation.

· Interactions between intrinsic organ neural networks and epithelial, immune, and endocrine cells, and their roles in metabolism and tissue homeostasis.

· Nervous-system-mediated inter-organ communication and physiological coordination.

· Multi-omics analysis, neural-activity imaging, and precise circuit manipulation of peripheral sensory and autonomic nervous systems.

· Central-peripheral nervous-system interactions in neurodegenerative disease, with emphasis on circuits underlying non-motor symptoms of Parkinson’s disease, peripheral proteotoxicity, bidirectional brain-body propagation, biomarkers, and intervention targets.