Significant Works:

1.Xu R, Ning Y, Ren F, Gu C, Zhu Z, Pan X, Pshezhetsky AV, Ge J, Yu J. Structure and mechanism of lysosome transmembrane acetylation by HGSNAT (2024). Nature Structural & Molecular Biology, In Press.

2. Yu J*, Rao P*, Clark S, Mitra J, Ha T and Gouaux E. Hippocampal AMPA receptor assemblies and mechanism of allosteric inhibition (2021). Nature, 594(7863):448-453. 

3. Yu J*, Zhu H*, Lape R, Greiner T, Du J, Lü W, Sivilotti L, Gouaux E. Mechanism of gating and partial agonist action in the glycine receptor (2021). Cell, 184:957-968.e21. 

4. Phulera S*, Zhu H*, Yu J*, Claxton DP, Yoder N, Craig Yoshioka C, Gouaux E. Cryo-EM structure of the benzodiazepine-sensitive α1β1γ2S tri-heteromeric GABAA receptor in complex with GABA (2018). eLife, 7:e39383.

5. Yu J.*, Zhang B, Zhang Y, Xu CQ, Zhuo W, Ge J, Li J, Gao N, Li Y, Yang M. A binding-block ion selective mechanism revealed by a Na/K selective channel (2018). Protein Cell, 9(7):629-639. 

6. Yu J*, Ge J*., Heuveling J, Schneider E, and Yang M. Structural basis for substrate specificity of an amino acid ABC transporter (2015). Proc Natl Acad Sci USA, 112, 5243-5248. 

7. Yu J*, Pian Y*, Ge J*, Guo J, Zheng Y, Jiang H, Hao H, Yuan Y, Jiang Y, and Yang M.  Functional and structural characterization of the antiphagocytic properties of a novel transglutaminase from streptococcus suis (2015). J. Bio. Chem, 290, 19081-19092.