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1.      Yan, L.; Zhang, T.; Wang, K.; Chen, Z.; Yang, Y.; Shan, B.; Sun, Q.; Zhang, M.; Zhang, Y.; Zhong, Y.; Liu, N.; Gu, J*.; Xu, D. *. SENP1 prevents steatohepatitis by suppressing RIPK1-driven apoptosis and inflammation. Nature Communications 2022, 13(1), 7153.


2.      Yang,Y.; Li, X.; Zhang, T.; Xu, D. *. RIP kinases and necroptosis in aging and aging-related diseases. Life Medicine, lnac003. (Review article)


3.      Xu, D.#; Zou, C.#; Yuan, J.*. Genetic regulation of RIPK1 and necroptosis. Annual Review of Genetics 2021, 55, 235-263. (Review article)


4.      Xu, D.#; Zhao, H.#; Jin, M.; Zhu, H.; Shan, B.; Geng, J.; Dziedzic, S. A.; Amin, P.; Mifflin, L.; Naito, M. G.; Najafov, A.; Xing, J.; Yan, L.; Liu, J.; Qin, Y.; Hu, X.; Wang,H.; Zhang, M.; Manuel, V. J.; Tan, L.; He, Z.; Sun, Z. J.; Lee, V. M. Y.;Wagner, G.; Yuan, J.*. Modulating TRADD to restore cellular homeostasis and inhibit apoptosis. Nature 2020, 587(7832), 133-138.


5.      Xu, D.#; Jin, T.#; Zhu, H.; Chen, H.; Ofengeim, D.; Zou, C.; Mifflin, L.; Pan, L.; Amin, P.; Li,W.; Shan, B.; Naito, M. G.; Meng, H.; Li, Y.; Pan, H.; Aron, L.; Adiconis, X.; Levin, J. Z.; Yankner, B. A.; Yuan, J.*. TBK1 suppresses RIPK1-driven apoptosis and inflammation during development and in aging. Cell 2018, 174 (6), 1477-1491. (Previewed in Cell 2018, 174(6), 1339-1341. Highlighted in Nat Cell Biol 2018, 20(12):1330-1331) 


6.      Xu, D. #; Liu, J. #; Fu, T.; Shan, B.; Qian, L.; Pan, L.*; Yuan, J.*. USP25 regulates Wnt signaling by controlling the stability of tankyrases. Genes & Development 2017, 31(10), 1024-1035.


7.      Xu, D.; Shan, B.; Sun, H.; Xiao, J.; Zhu, K.; Xie, X.; Li, X.; Liang, W.; Lu, X.; Qian, L.; Yuan, J.*. USP14 regulates autophagy by suppressing K63 ubiquitination of Beclin 1. Genes & Development 2016, 30(15), 1718-1730.


8.      Xu, D.; Shan, B.; Lee, B. H.; Zhu, K.; Zhang, T.; Sun, H.; Liu, M.; Shi, L.; Liang, W.; Qian, L.; Xiao, J.; Wang, L.; Pan, L.; Finley, D.; Yuan, J.*, Phosphorylation and activation of ubiquitin-specific protease-14 by Akt regulates the ubiquitin-proteasome system. eLife 2015,4, e10510.


9.      Xu, D.; Zhang, T.; Xiao, J.; Zhu,K.; Wei, R.; Wu, Z.; Meng, H.; Li, Y.; Yuan, J.*. Modification of BECN1 by ISG15 plays a crucial role in autophagy regulation by type I IFN/interferon. Autophagy 2015, 11(4),617-628.


10.   Xu, D.; Lu, C.; Chen, W.*. Palladium-catalyzed double arylations of terminal olefins in acetic acid. Tetrahedron 2012, 68(5), 1466-1474.


11.   Li W, Shan B, Zou C, Wang H, Zhang MM, Zhu H, Naito MG, Xu D, Manuel VJ, Mifflin L, Hou Z, Ravits J, Yuan J. *, Nuclear RIPK1 promotes chromatin remodeling to mediate inflammatory response. Cell Research. 2022, 32(7), 621-637.


12.   Mei, X., Guo, Y., Xie, Z., Zhong, Y., Wu, X., Xu, D., Li, Y., Liu N, Zhu, Z.*. RIPK1 regulates starvation resistance by modulating aspartate catabolism. Nature Communications. 2021, 12(1):6144.


13.   Naito, M. G.; Xu, D.; Amin, P.; Lee,J.; Wang, H.; Li, W.; Kelliher, M.; Pasparakis, M.; Yuan, J.*. Sequential activation of necroptosis and apoptosis cooperates to mediate vascular and neural pathology in stroke. PNAS 2020, 117(9), 4959-4970.


14.   Li, F.; Xu, D.; Wang, Y.; Zhou, Z.;Liu, J.; Hu, S.; Gong, Y.; Yuan, J.; Pan, L.*. Structural insights into the ubiquitin recognition by OPTN (optineurin) and its regulation by TBK1-mediated phosphorylation. Autophagy 2018, 14 (1), 66-79.


15.   Zhu, K.; Liang, W.; Ma, Z.; Xu, D.;Cao, S.; Lu, X.; Liu, N.; Shan, B.; Qian, L.; Yuan, J.*. Necroptosis promotes cell-autonomous activation of proinflammatory cytokine gene expression. Cell Death & Disease 2018, 9(5), 500.


16.   Geng, J.; Ito, Y.; Shi, L.; Amin, P.; Chu, J.; Ouchida, A. T.; Mookhtiar, A.K.; Zhao, H.; Xu, D.; Shan, B.; Najafov, A.; Gao, G.; Akira, S.; Yuan, J.*. Regulation of RIPK1 activation by TAK1-mediated phosphorylation dictates apoptosis and necroptosis. Nature Communications 2017, 8(1), 359.


17.   Zhang, T.; Dong, K.; Liang, W.; Xu, D.;Xia, H.; Geng, J.; Najafov, A.; Liu, M.; Li, Y.; Han, X.; Xiao, J.; Jin, Z.;Peng, T.; Gao, Y.; Cai, Y.; Qi, C.; Zhang, Q.; Sun, A.; Lipinski, M.; Zhu, H.;Xiong, Y.; Pandolfi, P. P.; Li, H.; Yu, Q.; Yuan, J.*. G-protein-coupled receptors regulate autophagy by ZBTB16-mediated ubiquitination and proteasomal degradation of Atg14L. eLife 2015, 4, e06734.


18.   Xiao, J.; Zhang, T.; Xu, D.; Wang, H.; Cai, Y.; Jin, T.; Liu, M.; Jin, M.; Wu, K.; Yuan,J.*. FBXL20-mediated Vps34 ubiquitination as a p53 controlled checkpoint in regulating autophagy and receptor degradation. Genes & Development 2015, 29(2), 184-196.


19.   Liu, B.; Zhang, Y.; Xu, D.; Chen, W.*. Facile synthesis of metal N-heterocyclic carbene complexes. Chemical Communications 2011, 47(10), 2883-2885.


20.   Gu, S.; Xu, D.; Chen, W.*. Heterobimetallic complexes containing an N-heterocyclic carbene based multidentate ligand and catalyzed tandem click/Sonogashira reactions. Daltontransactions 2011, 40(7), 1576-1583.


(#equal contribution, *corresponding)


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